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A.LicznerskiP.et al

At higher exposures these findings were associated with moderate to marked adverse clinical signs (lethargy, abnormal respiration, ataxia, reduced activity, body tone and reflexes) and marked decreases in plasma and CSF glucose levels

This finding suggests that semaglutide injections may be beneficial for establishing menstrual cycle regularity in this population

In contrast, our evidence suggested that the cAMP-PKA signaling pathway mediates the exendin-4-induced inhibition in GCs

It has been suggested that the vagus nerve mediates the aversive effects of GLP-1, as ip injection of exendin-4 induces CFA in vagotomised but not sham-operated rats [151]