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Weight loss itself can restore fertility in individuals with obesity-related infertility by improving insulin sensitivity and reducing excess androgens that disrupt ovulation
[16] [17] Pharmacological management may be appropriate for persistent symptoms
The American College of Rheumatology (ACR) recommends early aggressive therapy to prevent irreversible joint damage and achieve remission or low disease activity using a treat-to-target approach with regular monitoring of disease activity measures
Both appear in research and practitioner protocols
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