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For ischemic stroke and retinal damage, two major complications of diabetes mellitus, it was shown that DPP-4 inhibition prevented inflammation and mediated neuroprotective effects (68, 89)

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Across seven randomized controlled trials involving nearly 5,000 participants, tirzepatide at its highest 15 mg dose produced an average weight loss roughly 11.83 percentage points greater than placebo, with an absolute difference of about 11.5 kg in body weight

While compounded semaglutide contains the same active ingredient as brand-name drugs like Wegovy, there are important differences