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For example, a 250-pound patient on semaglutide might lose 40 to 55 pounds, compared to 3 to 5 pounds on metformin alone

Drugs are not metabolized by the liver, but multidrug and toxin extrusion protein 1 (MATE1) expressed in hepatocytes is involved in the clearance of drugs, which is transported to the kidney through bile or through blood (Gong et al., 2012)

Drug Targets 11 (2), 9298 (2011)

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Within six months of its debut, Mounjaro became the second-highest-selling drug in India, recording sales worth 80 crore in September, according to data from marketing intelligence and analytics firm Pharmarack