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The latest SUSTAIN trial was published in 2022 that showed semaglutide once a week led to greater HBA1C reduction as compared to insulin aspart thrice per day

J Clin Endocrinol Metab (2015) 100(4):E61622.10.1210/jc.2014-4244 98 KoutroubakisIEOustamanolakisPMalliarakiNKarmirisKChalkiadakisIGanotakisEet alEffects of tumor necrosis factor alpha inhibition with infliximab on lipid levels and insulin resistance in patients with inflammatory bowel disease

The databases searched included PubMed, Embase, OVID, CINAHL, and Cochrane

Additionally, these medications are not recommended during pregnancy or while breastfeeding

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