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Why the CNS Gets Overloaded As bodybuilders grow stronger, the weights they move become heavier and more demanding

c , Heart weights of mice in Extended Data Figs

The medication is not failing you

One plausible mechanism is a direct effect on the sinus node, the hearts natural pacemaker, where GLP-1 receptors can alter pacemaker activity

Semaglutide, a GLP-1 receptor agonist originally developed for type 2 diabetes management, has emerged as a treatment option for chronic weight management in adults with obesity or overweight conditions
