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For obesity management, NICE technology appraisal TA875 recommends semaglutide (Wegovy) only within specialist weight management services, for people with a BMI of at least 35 kg/m (or 30 kg/m with weight-related comorbidities) and as part of a programme including diet and physical activity for a maximum of 2 years

Back La Barre, J, Still, EU (Jan 1930) 'Studies on the physiology of secretin

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Cardiovascular safety of incretin-based therapies in type 2 diabetes: systematic review of integrated analyses and randomized controlled trials

In the NTS, neurons expressing GLP-1 also express the leptin receptor [351,353]