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47 While lifestyle modifications, regular physical activity and diet are recommended for all HF patients, weight reduction should be a direct therapy goal for patients with HFpEF and obesity

Modern advances in long-acting peptide design, biased agonism, receptor de-orphanization, and systems pharmacology fundamentally alter the riskbenefit calculus of these targets
10.1210/en.2016-1334 264

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For exercise: hotel gyms, bodyweight circuits, walking tours, and swimming all maintain your routine
