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doi: 10.1530/EJE-06-0756

In a phase 2 study, amycretin showed a mean weight reduction of up to 24.3%, which is comparable to or even greater than the weight loss seen with tirzepatide and similar to the results for retatrutide

( 10.1016/j.cmet.2019.01.004) [DOI] [PMC free article] [PubMed] [Google Scholar] 96.American Diabetes Association

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Ideal candidates include adults with: BMI 30 (obesity) BMI 27 with weight-related conditions (type 2 diabetes, hypertension, high cholesterol, sleep apnea, PCOS) Inability to lose weight through diet and exercise alone Contraindications include: Personal or family history of medullary thyroid carcinoma Multiple endocrine neoplasia syndrome type 2 (MEN 2) History of pancreatitis (caution advised) Your online doctor will evaluate all risks and benefits before prescribing