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Paradoxically, despite the absence of thermogenesis via mitochondrial uncoupling, UCP1 null mice are not more susceptible to weight gain than wild-type mice on a high-fat diet, even when housed at thermoneutrality (30C) [123]

First-line management includes drinking 1.52 litres of fluids daily, using paracetamol (maximum 4 g daily) or ibuprofen (maximum 1.2 g daily for over-the-counter use) as appropriate, and resting in a quiet environment

Specific types are most commonly treated with sulfonylurea, particularly those identified as HNF4A-MODY and HNF1A-MODY

FSA/HSA eligible

[DOI] [PMC free article] [PubMed] [Google Scholar] 30.Castela ., Costa C