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Most people report that their gastrointestinal side effects improve within 46 weeks as their body adapts to semaglutide, especially if they actively avoid high-fat and high-sugar foods during this adjustment period

Although glucagon-like peptide-1 (GLP-1) receptor agonists and sodium-glucose cotransporter-2 (SGLT2) inhibitors are increasingly used as second-line agents, direct comparisons between these treatments are insufficient

In week 4, you will notice significant appetite suppression, weight changes (due to loss of fat mass), less bloating, and elevated energy levels

Reduced calorie intake may affect energy levels, especially early in treatment

NAION typically causes permanent vision loss