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Description
Why the new trial matters The TAG-MS trial, reported by Multiple Sclerosis News Today on May 7, is structured to address the mechanism question directly

SGLT2i and GLP-1 RA Therapy in Type 1 Diabetes and Reno-Vascular Outcomes: A Real-World Study

A statistically significant improvement in KCCQ-CSS was found in the semaglutide group compared with placebo, although the magnitude of improvement was numerically smaller than in STEP-HFpEF

This work set out to discover how GLP-1 mitigates cholesterol-induced lipotoxicity in hepatocytes and what mechanisms are at play in this process
When the face loses fat, it may result in a gaunt or aged appearance
