retatrutide type 2 diabetes trial results 2024 2025 Results: 28.3% Weight Loss Data Retatrutide Phase 2 NEJM Trial:

The approval was based on data from two randomized, double-blind, placebo-controlled studies involving more than 3,000 overweight or obese adults

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Appetite effects: Act on brain regions controlling hunger and fullness Reduce appetite between meals Enhance feelings of satisfaction after eating Decrease food preoccupation and cravings Gastric effects: Slow stomach emptying Prolong feelings of fullness Reduce the volume of food needed to feel satisfied Metabolic effects: Improve insulin secretion (glucose-dependent) Reduce glucagon release Improve insulin sensitivity Both Saxenda and Ozempic work through these mechanisms

These drugs may even be able to treat alcohol addiction