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Obesity and cardiovascular disease: a scientific statement from the American Heart Association

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Since tirzepatide inherently slows gastric emptying as part of its mechanism of action, administering it to patients with pre-existing gastroparesis could potentially worsen their condition and lead to severe gastrointestinal complications

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For detailed stability information on specific semaglutide formulations, how long semaglutide remains effective and whether semaglutide expires after 28 days provide granular details that parallel the tirzepatide information in this guide