can you go back and forth between semaglutide and tirzepatide vs. Tirzepatide: What's the Difference Which Is Right for You?: Envizion Medical: Wellness Center Switching from semaglutide to tirzepatide
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References Harding, J

Tirzepatide, on the other hand, is a dual-acting GIP and GLP-1 receptor agonist, which means it targets both GIP and GLP-1 receptors to enhance insulin secretion and promote satiety

References West S, Scragg J, Aveyard P, et al
In 2017, a small single-center randomized trial of 62 participants, but with longer follow-up, found benefit with exenatide given once weekly (see graph below)