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GLP-1R Agonist Exendin-4 Protects Against Hemorrhagic Transformation Induced by rtPA After Ischemic Stroke via the Wnt/beta-Catenin Signaling Pathway
A study has shown that high expression of DPP-4 is not only found in intestinal epithelial brush border, but also in endothelial cells ( via renal elimination
In contrast to mice that were administered AC3174, mice that had similar reductions in body weight due to calorie restriction showed marginal reductions in LFC, suggesting that the decrease in LFC achieved by GLP-1RAs was not fully dependent on weight loss
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