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Cardiovasc Diabetol 21(1):232 Hu Y et al (2022) Cost-effectiveness analysis of 4 GLP-1RAs in the treatment of obesity in a US setting

It enrolled 17,604 adults aged 45 or older with a body mass index (BMI) of 27 kg/m2 or greater and preexisting CVD (prior MI, prior stroke or peripheral artery disease) without diabetes

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This approach is similar to how some injectable GLP-1 therapies, like Saxenda , have also been used for weight management in non-diabetic patients

The symptoms that commonly improve include: Reduced flushing and hives Decreased gastrointestinal distress Improved respiratory symptoms Better tolerance to environmental triggers Stabilized blood pressure Reduced brain fog and cognitive issues Decreased joint pain and inflammation The Importance of Starting Low and Going Slow One crucial insight from the research is the importance of dosing strategy