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While IGBs are an established endoscopic intervention for weight loss, the impact of combining IGB insertion with semaglutide, a GLP-1 receptor agonist, remains unclear

This is a legitimate worry because traditional calorie restriction, even without medications, typically results in some degree of lean tissue loss alongside fat loss

Comparative effectiveness of glucose-lowering drugs for type 2 diabetes: A systematic review and network meta-analysis

Pharmacological strategies targeting multiple pathways have shown synergistic benefits in metabolic disease models
