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Although Semaglutide is shown to be effective in lowering weight, HbA1c levels, and reducing cardiovascular risk, there are many side effects of this medication that should be closely monitored

Allulose consumed with carbohydrate-containing meals may interact with glucose-sensing mechanisms in enteroendocrine cells, potentially enhancing or modifying the incretin response

therefore, FDA is continuing to look into this issue. The majority of real-world studies using electronic health records reached the same conclusion (11)

C., & Callahan, E

For example, in the SUSTAIN 5 clinical trial, patients with HbA1c levels of 8.0% or lower had their basal insulin doses reduced by 20% when starting semaglutide therapy to minimize the risk of low blood sugar