glp 1 agonist stands for Everyone is talking about GLPs. But do you know the difference between them?⁠ ⁠ Semaglutide. Tirzepatide. Retatrutide. Three different medications. Three different mechanisms. And one thing they all have in common: they List of GLP-1 Receptor Agonists

CONTRAINDICATIONS History of hypersensitivity reaction to tirzepatide or any of its excipients Personal or family history of medullary thyroid carcinoma (MTC) Multiple Endocrine Neoplasia syndrome type 2 (MEN 2) PRECAUTIONS Kidney disease No dose adjustment is recommended in patients with any degree of renal impairment Liver disease No dose adjustment is recommended in patients with any degree of liver disease Stomach disorders Tirzepatide slows gastric emptying and is not recommended in patients with significant stomach disorders, including diabetic gastroparesis General anesthesia or deep sedation GLP-1 therapies, like tirzepatide, slow gastric emptying, possibly increasing the risk of residual gastric contents and pulmonary aspiration in patients receiving anesthesia or deep sedation for procedures

Out-of-pocket costs for GLP-1 therapies can be substantial, often exceeding what many individuals can sustain over time

When it is combined with other diabetes medications, particularly insulin and insulin secretagogues, hypoglycemia can occur

However, challenges including high costs exceeding $1000 per month, gastrointestinal side effects, nutritional deficiencies, and low long-term adherence with subsequent weight regain [5] [6] warrant careful consideration

1) Cancer and Thyroid Concerns Semaglutide is also not recommended for people with a family or medical history of medullary thyroid carcinoma (MTC), medullary thyroid cancer, and thyroid tumors or those with Multiple Endocrine Neoplasia syndrome type 2