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"That rebound weight gain can really fuel guilt, shame and body dissatisfaction, which can then push people into those disordered behaviours to try to lose weight again." Even for people not using the medications, media coverage "celebrating weight loss" and showing "before and after" pictures can also contribute to disordered eating, she said

Perform the entire reconstitution on an ice pack or inside a refrigerator to keep the solution below 8C throughout the process

Shigeto M, Katsura M, Matsuda M, Ohkuma S, Kaku K

Repeatedly injecting into the same spot can lead to lipohypertrophy a localised thickening or hardening of fatty tissue which can impair drug absorption and reduce the medication's effectiveness

In addition to cross resistance with other macrolides (erythromycin and clarithromycin), ribosomal modification may determine resistance to other antibiotic classes (lincosamides and streptogramins B) that bind to overlapping ribosomal sites