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A critical pathway is the suppression of CCK secretion, a hormone necessary for normal gallbladder contraction
But the downstream key events (adipose remodeling, neuroplasticity, cardiac fibrosis reduction, renal protection) and the organism-level outcomes (cardiovascular mortality reduction, weight loss maintenance, cognitive function) require integrated biological systems
10.1016/j.gene.2017.08.008 [DOI] [PubMed] [Google Scholar] Liu W.-L., Chang J.-M., Chong I.-W., Hung Y.-L., Chen Y.-H., Huang W.-T., et al
