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At the same time, transformation stories online often underplay the less glamorous realities: Muscle loss alongside fat loss Nutritional compromise from severely reduced intake Hair loss, fatigue, nausea, and GI adverse effects Weight regain after discontinuation Psychological pressure surrounding body image Unsupervised or socially influenced use Perhaps the most important point: these medications were never meant to replace lifestyle modification

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By Abigail Brooks Eli Lilly and Company has announced positive topline results from the phase 3 TRIUMPH-4 clinical trial assessing the safety and efficacy of the 2 largest investigational doses of retatrutide in adults with obesity or overweight and knee osteoarthritis, and without diabetes, as an a