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Apart from improvements in multiple cardiometabolic risk factors, tirzepatide also improves various obesity-related complications such as obstructive sleep apnoea (OSA), metabolic dysfunction-associated steatohepatitis (MASH) and heart failure with preserved ejection fraction [28,29,30]

Additionally, mazdutide has been tested in head-to-head trials against semaglutide, providing insight into how it performs against the most widely used GLP-1 agonist

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