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These findings demonstrate the drugs potential to improve overall metabolic health and address obesity-related diseases such as liver dysfunction and metabolic dysfunction-associated steatohepatitis (MASH)

Recurrent nocturnal hypoxic episodes promote oxidative stress and inflammatory activation, characterized by elevated TNF- , IL-6, and C-reactive protein levels ( 4.4 Potential effects of tirzepatide on upper airway function In addition to metabolic and inflammatory modulation, emerging evidence suggests that incretin-based therapies may influence upper airway neuromuscular control

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The primary goal for using semaglutide for weight loss should be to avoid weight regain and balance metabolic activity