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semaglutide prediabetes progression to diabetes step trial once a week in adults with overweight or obesity, with or without type 2 in an east Asian population (STEP 6): a randomised, double-blind, double-dummy, placebo-controlled, phase 3a Maximizing Semaglutide: Understanding the Doses

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Dong C, Yu J, Yang Y, Zhang F, Su W, Fan Q, Wu C, Wu S

semaglutide prediabetes progression to diabetes step trial once a week in adults with overweight or obesity, with or without type 2 in an east Asian population (STEP 6): a randomised, double-blind, double-dummy, placebo-controlled, phase 3a Maximizing Semaglutide: Understanding the Doses

Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist approved by the FDA for managing type 2 diabetes (under the brand name Ozempic) and chronic weight management (Wegovy)

semaglutide prediabetes progression to diabetes step trial once a week in adults with overweight or obesity, with or without type 2 in an east Asian population (STEP 6): a randomised, double-blind, double-dummy, placebo-controlled, phase 3a Maximizing Semaglutide: Understanding the Doses

So perhaps meeting recommended nutrient intakes remains achievable

semaglutide prediabetes progression to diabetes step trial once a week in adults with overweight or obesity, with or without type 2 in an east Asian population (STEP 6): a randomised, double-blind, double-dummy, placebo-controlled, phase 3a Maximizing Semaglutide: Understanding the Doses

Less common but more serious risks include pancreatitis (0.2-0.3% per year), gallbladder disease (1-2% per year), and acute kidney injury from severe dehydration

semaglutide prediabetes progression to diabetes step trial once a week in adults with overweight or obesity, with or without type 2 in an east Asian population (STEP 6): a randomised, double-blind, double-dummy, placebo-controlled, phase 3a Maximizing Semaglutide: Understanding the Doses

Genetic and metabolic factors may influence how someone's body responds to GLP-1 agonism

semaglutide prediabetes progression to diabetes step trial once a week in adults with overweight or obesity, with or without type 2 in an east Asian population (STEP 6): a randomised, double-blind, double-dummy, placebo-controlled, phase 3a Maximizing Semaglutide: Understanding the Doses

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