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Moreover, studies with a longer follow-up are needed for the evaluation of oral semaglutide with regard to microvascualr or macrovascular complications of DM, cardiovascular disease as well as mortality and morbidity

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While myriads of pharmacotherapies are licensed to treat adults with T2D, treatments accessible to children and adolescents have been limited until recently

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Experimental designs assess doseresponse, titration schedules, and durability of weightrelated outcomes over months [2,6]