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These findings suggest that Retatrutide may ameliorate HFD-induced adipose tissue dysfunction in mice by modulating the biological pathways associated with lipid metabolism, inflammation-immunity, and adipose tissue remodeling

Eligibility thresholds are lower than NHS criteria, typically requiring a BMI of 30 or above, or 27 with weight-related health conditions

Semaglutide is the active ingredient in Ozempic, Wegovy, and Rybelsus, but the drugs have different approvals and different usages according to the manufacturer and the FDA

doi: 10.1111/bph.13513