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triple glp 1 gip glucagon receptor agonist GLP-1/GIP/Glucagon Retatrutide Explained: How the Triple
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Diabetes 63 , 32213229
Journal reference: Rodriguez, M

The mechanism of action of GLP-1RA to promote weight loss mainly includes the reduction of fat deposition through regulation of adipose tissue (lipolysis, fatty acid oxidation, and adipocyte differentiation) and the reduction of food intake through the central and peripheral nervous system

However, this evidence is limited, inconsistent, and does not demonstrate clinically significant effects comparable to prescription GLP-1 agonists