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GLP-1 administration modulates the phosphorylation state of calcium cycling proteins in the sinus node We speculated that the increased heart rate may result from phosphorylation changes elicited in the pacemaker cells expressing GLP-1R

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Finney encourages his patients to eat small meals slowly and avoid heavy or greasy foods to minimize nausea, and to pick fiber-rich foods and drink plenty of water to reduce constipation

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