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However, there have been few studies on the potential mechanism of the action of GLP-1RAs in the treatment of PCOS
They identified nearly 70,000 users who said they were taking drugs such as semaglutide (Ozempic, Wegovy) or tirzepatide (Mounjaro, Zepbound)
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19 The Effect of GLP-1RAs on Blood Pressure A meta-analysis of 16 RCTs showed that use of GLP-1RAs leads to a moderate BP reduction in patients with hypertension
However, as mentioned earlier, tirzepatide uniquely binds both the GLP-1R and the GIPR, but only GIPRs are found on human adipocytes [29]
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