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No human data on the excretion of GLP-1 agonists or SGLT2 antagonists in milk are available, but in rat and mouse models excretion in milk was observed with concomitant effects on neonatal growth of GLP-1 agonists

GIP activation may also improve lipid processing and growth of white adipose tissue, resulting in complementary processes

The Federal Register notice for this proposal was published in early May 2026

None of these approaches have been validated in clinical trials
