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Description
GLP-1, short for glucagon-like peptide-1, is a hormone that helps regulate blood sugar levels, appetite, and digestion
Not everyone needs the maximum dose
Notably, SCFA-mediated GLP-1 release was abolished in Gpr43 -deficient mice, confirming receptor dependency (Psichas et al., 2015)
In this review article, we discuss the mechanistic and clinical synergies that make the combined use of GLP-1RAs and SGLT2is appealing in patients with T2DM
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