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Only a subset of the Baby Boomers was reaching an age where cardiovascular risks were rising

Ryan said that "we do need better evidence" around whether some individuals can maintain weight loss after coming off GLP-1s, but she thinks what "Calibrate is doing is sharing the decision-making with the patient and trying to adapt to the environment where drugs may not always be available." Since Calibrate has come onto the market, results were published from a much larger, peer-reviewed study funded by the Ozempic manufacturer Novo Nordisk in 2022

Sometime after, in 2021, Wegovy was released as a weight loss medication