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The oral version was previously available for diabetes management (under the brand name Rybelsus), but this new FDA approval specifically authorizes a high-dose oral formulation for chronic weight management

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If you swallow it too early, the potent medication gets sent to your stomach, where digestive acids can degrade it and significantly reduce its bioavailability and effectiveness

I gained about two kilos back over a period of 18 months

This may explain why AMPAR activation continues even after blocking 5-HT2A receptors with ketaserin