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The incorporation of both GIP and GLP-1 receptor stimulation demonstrated a more pronounced synergistic effect on insulin signaling pathways comparable to monotherapy [26]

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It would be another decade before these medications would be discovered, and two before the shot heard round the world would revolutionize the care for people with diabetes, excess fat (diagnosed with obesity), sleep apnea and more along with the diet and food industries, pharmaceutical care, dietary supplementation and fitness recommendations

It activates the GLP-1 receptor only, not the GIP receptor