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Once a pen has been opened and used for its first dose, it can be stored either in the refrigerator or at room temperature (below 77F / 25C) for up to 56 days

Patients may not achieve expected HbA1c reductions or weight loss outcomes if using heat-damaged medication

Results PH is driven by multifactorial mechanisms, including exaggerated insulin secretion, incretin overproduction (GLP-1, GIP), altered glucose absorption, and autonomic dysfunction
People who are overweight or have obesity can become insulin-resistant, which means the body doesnt respond to insulin properly
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