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the medication is contraindicated in patients with personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2 [1] Oral contraceptives : Tirzepatide can reduce exposure to oral contraceptives

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Yes, glipizide and Rybelsus (semaglutide) can be prescribed together for the management of type 2 diabetes mellitus, though this combination requires careful clinical consideration and monitoring