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Lower Risk of Substance Use Disorders Across Multiple Substances Patients treated with GLP-1 receptor agonists showed lower risk of developing several forms of substance use disorder compared with those receiving other diabetes medications

This study was limited in scope: Conducted on 24 rats, not humans Administered a single dose Designed only to demonstrate that some absorption is possible Importantly, the study itself includes this disclaimer: This proof-of-concept study is not intended to provide guidance on the sublingual dosing of semaglutide in humans, or dosing conversion from other forms to sublingual administration. This means the only research behind these products cannot confirm whether they work in humans or provide guidance on appropriate dosing