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Then, the animals proceeded to a PR schedule of reinforcement where they were tested across 4 sessions at variable doses of fentanyl (0-10 g/kg/inf, i.v.) in a randomized order while receiving a stable dose of semaglutide (0.1 mg/kg, s.c.) or vehicle (0.9% saline, s.c.)

Patients typically report reduced cravings, fullness after smaller meals, greater energy levels, and enhanced blood sugar, cholesterol, and blood pressure metrics soon after starting semaglutide

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10.1016/j.glmedi.2025.100183 5 CameronG.ChandraR