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They mimic the action of the naturally occurring hormone GLP-1, which is involved in regulating blood sugar levels

Moreover, GLP-1RA and DPP-4 inhibitors are approved for the treatment of T2DM and exhibit potential pleiotropic effects on the heart and kidneys, which may be independent of or dependent on the hypoglycemic effects

However, metformin (category B) is generally preferred during pregnancy, whereas GLP-1 receptor agonists like Rybelsus are contraindicated in pregnancy

Your body adapts and then they go away, Azagury said

The main drug class of GLP-1 receptor agonist is liraglutide, dulaglutide, lixisenatide, and others