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Another important consideration when evaluating the impact of these medications on bone health outcomes is the sustainability of GLP1Ra use as weight regain following cessation of treatment is expected (Quarenghi et al., 2025)

Pharmacologic approaches to glycemic treatment: standards of medical care in diabetes-2022

Hormone Replacement Therapy Hormone replacement therapy (HRT), including testosterone replacement therapy (TRT) for men and hormone therapy for women, requires comprehensive medical evaluation and ongoing monitoring by qualified healthcare providers

Experts think this means itll be even more effective in terms of weight loss, Wojeck said
