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A phase 4 trial (NCT05181475) was initiated in December 2021 to examine the long-term efficacy and safety of GV-971 as well as changes in blood and gut microbiota biomarkers and thereby validate its mechanism of action and establish guidance for the more rational use of drugs in clinical practice

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Without that bridge, milligrams and units are two languages that do not translate

Key facts about retatrutide: Chemical class 39-amino-acid synthetic triple agonist (GLP-1 + GIP + glucagon receptor) Molecular weight approximately 4731 Da Developer Eli Lilly Half-life approximately 6 days (supports weekly dosing) Form typically supplied as lyophilized powder