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doi: 10.1001/jama.2023.24945 5 BezinJ.Bnard-LaribireA.HucteauE.TournierM.MontastrucF.ParienteA.et al

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NMR, circular dichroism (CD) spectroscopy, and X-ray crystallography studies show that GLP-1 is unstructured in aqueous solution, but adopts a helical structure in a membrane-like environment and by binding to its receptor (Thornton and Gorenstein, 1994
