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Rates of ischemic optic neuropathy were similar between groups at each time point, with no statistically significant differences observed

Therefore, further large-scale studies are needed to further explore the therapeutic efficacy of GLP-1R agonists in patients with DPN

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For procedures requiring gastric emptying or precise timing of oral medication administration, such as upper endoscopy or surgery requiring general anesthesia, the delayed gastric emptying effect of semaglutide may need to be considered

Semaglutide belongs to a class of drugs known as glucagon-like peptide-1 receptor agonists (GLP-1 RAs), which mimic the action of the naturally occurring hormone GLP-1 produced in the intestines