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Description
Main Contributing Factors to the Obesity Epidemic The origin of this pandemic is profoundly multifactorial and goes far beyond a simple energy balance equation, emerging from a complex interplay between behavioral, environmental, and biological factors that act upon a foundation of individual susceptibility [8]

A number of studies have reported on surgical re-intervention in the treatment of severe hypoglycaemia in patients after RYGB using a variety of surgical techniques (such as bypass reversal, pouch restriction and interposed intestinal loops), with variable outcomes 135,136,137,138,139,140,141,142,143,144,145

In studies with multiple treatment arms, including combination therapies and monotherapies with either SGLT-2i, GLP-1RA, or TAU, we restructured these into separate comparisons

Different pharmacological options may be used together to target various aspects of the condition, including hyperandrogenism and dyslipidemia

Stark J, Klass MJ, Owen L
