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The clinical history a patient brings, the laboratory work the clinician runs, the lived response that emerges over months on a given molecule, and the priorities the patient articulates, all of those things matter at least as much as the genetic prior, and frequently more

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14.2 Use in Pregnant Women 14.2.1 Potential Risks to Fetus Limited data exist regarding fetal safety

The harder question which drugs survive to commercial practice at accessible prices will play out over the next 18 months as FDA submissions accumulate and payers begin drawing their formulary red lines