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Description
In the SURMOUNT-1 program summarized in the EMA product information, tirzepatide produced mean body-weight reductions of 16.0%, 21.4% and 22.5% at 72 weeks across the 5 mg, 10 mg and 15 mg groups, versus 2.4% with placebo
Featured image: GLP-1 agonists
By this dual approach, it amplifies the benefits seen with GLP-1 agonists by targeting both incretin pathways (Rizvi and Rizzo 2022)
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Strong evidence supports their efficacy in inducing clinically meaningful weight loss in individuals with overweight or obesity
