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Anatomical images were acquired using a T 2 -Turbo-RARE scan, TR = 2230 ms, TE = 39.43 ms, FOV = 20 7.9 mm 2 , slices: 23, slice thickness = 0.3 mm, matrix size = 200 79

Recognising these patterns helps patients understand that plateaus are temporary and that continued adherence to treatment and lifestyle modifications will eventually lead to resumed progress

This extends beyond specific tastes to encompass reduced motivation to eat altogether

In a study looking at the drug tirzepatide, people lost an average of 15%-20% of their body weight

In the SELECT trial, 2.4 mg semaglutide weekly or placebo was administered to over 16,000 patients with overweight/obesity and established cardiovascular disease (85)