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Compounded prescriptions are technically eligible if prescribed for a qualifying medical condition (obesity, type 2 diabetes), but many HSA/FSA platforms require additional documentation: a Letter of Medical Necessity from the prescribing clinician, the compounded prescription receipt with NDC or compounding code, and sometimes prior approval

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Pregnancy and breastfeeding are handled differently across products, with the weight-management versions generally advised against during pregnancy

Even a slight miscalculation can affect results or cause unwanted side effects